Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2039219 | 0.94 | PARP1 (0.38) | PARP1POLBHCAR2CES2CES1 | |
| SCHEMBL6133362 | 0.85 | POLB (0.47) | POLBHCAR2ALDH1A1TSHRCA1 | |
| SCHEMBL29912760 | 0.85 | TPMT (0.44) | PARP1POLBHCAR2GPR35 | |
| SCHEMBL986020 | 0.85 | TPMT (0.44) | PARP1POLBHCAR2GPR35 | |
| SCHEMBL31327392 | 0.84 | CES2 (0.44) | PARP1POLBHCAR2CES2CES1 | |
| SCHEMBL3397238 | 0.84 | PARP1 (0.32) | PARP1POLBHCAR2CES2CES1 | |
| SCHEMBL10262794 | 0.84 | PARP1 (0.32) | PARP1POLBHCAR2CES2CES1 | |
| SCHEMBL5225361 | 0.84 | CES2 (0.44) | PARP1POLBHCAR2CES2CES1 | |
| SCHEMBL15700662 | 0.84 | TPMT (0.43) | PARP1POLBHCAR2GPR35NOTUM | |
| SCHEMBL5223098 | 0.79 | MEN1 (0.41) | GPR35CA1CA2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-111545249-B | Preparation method of conjugated microporous polymer/palladium-nickel bimetallic catalyst | 齐齐哈尔大学 | 2023-03-21 | — | — | CN | claimed |
| CN-111545249-A | Preparation method of conjugated microporous polymer/palladium-nickel bimetallic catalyst | 齐齐哈尔大学 | 2020-08-18 | — | — | CN | claimed |
| CN-122029155-A | Heterocyclic compound and harmful arthropod control composition containing same | 住友化学株式会社 | 2026-05-12 | — | — | CN | disclosed |
| US-12559461-B2 | Antibiotic adjuvant compounds | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2026-02-24 | — | — | US | disclosed |
| CN-120064244-A | SERS detection platform based on nanoparticle assembly and pH detection method | 南京邮电大学 | 2025-05-30 | — | — | CN | disclosed |
| WO-2025089403-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2025-05-01 | — | — | WO | disclosed |
| WO-2025079605-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2025-04-17 | — | — | WO | disclosed |
| CN-115385902-B | Benzimidazole compound, and preparation method and application thereof | 徐州医科大学 | 2024-03-29 | — | — | CN | disclosed |
| US-20230286922-A1 | ANTIBIOTIC ADJUVANT COMPOUNDS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2023-09-14 | — | — | US | disclosed |
| EP-3162806-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | LT MATERIALS CO LTD (KR) | 2023-08-23 | — | — | EP | disclosed |
| US-4403057-A | Diester of 3,5,3',5'-tetrabromo-bisphenol A with halogenated aromatic carboxylic acid | ASAHI-DOW LIMITED (JP) | 1983-09-06 | — | — | US | disclosed |
| US-4310680-A | METAL OR METAL COMPOUND CATALYST | DYNAMIT NOBEL AG (DE) | 1982-01-12 | — | — | US | disclosed |
| US-4301062-A | Diester of 3,5,3',5'-tetrabromo-bisphenol A with halogenated aromatic carboxylic acid | ASAHI DOW LIMITED (JP) | 1981-11-17 | — | — | US | disclosed |
| EP-0031436-A2 | A method for the cleavage of siloxanes | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1981-07-08 | — | — | EP | disclosed |
| US-4057553-A | COLOR AGENT FOR FOODS, VITAMINS AND DRUGS | HOFFMANN-LA ROCHE INC. (US) | 1977-11-08 | — | — | US | disclosed |
| US-3959216-A | N-(Halobenzoyl) hexahalo-3,5-methanotetrahydrophthalimides | VELSICOL CHEMICAL CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |
| US-3959217-A | N-(halobenzoyl)-4,5-dibromo-3,6-methanohexahydrophthalimides | VELSICOL CHEMICAL CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |
| US-3953397-A | N-(halobenzoyl)-3,4-dibromohexahydrophthalimides | VELSICOL CHEMICAL CORPORATION (US) | 1976-04-27 | — | — | US | disclosed |
| US-3950307-A | FIREPROOFING POLYMERS | VELSICOL CHEMICAL CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286922-A1 | ANTIBIOTIC ADJUVANT COMPOUNDS | MYD88, TLR5, TLR8 | PARP1 3913/4885POLB 3931/4885HCAR2 2184/4885 |
| US-12559461-B2 | Antibiotic adjuvant compounds | MYD88, TLR5, TLR4 | PARP1 4393/4885POLB 4634/4885HCAR2 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.