Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882382 | 1.00 | RIPK1 (0.67) | RIPK1KDM4EALDH1A1PTGDR2RAB9A | |
| SCHEMBL22447818 | 0.81 | KDM4E (0.48) | RIPK1KDM4EALDH1A1PTGDR2RAB9A | |
| SCHEMBL17882287 | 0.80 | RIPK1 (1.00) | RIPK1KDM4EALDH1A1 | |
| SCHEMBL22447788 | 0.76 | CNR2 (0.56) | KDM4EALDH1A1RAB9A | |
| SCHEMBL14630008 | 0.74 | PTGDR2 (0.54) | RIPK1KDM4EALDH1A1PTGDR2 | |
| SCHEMBL21362892 | 0.72 | BCHE (0.49) | KDM4EALDH1A1 | |
| SCHEMBL3628742 | 0.72 | BCHE (0.49) | KDM4EALDH1A1 | |
| SCHEMBL29912752 | 0.71 | RIPK1 (0.50) | RIPK1KDM4EALDH1A1 | |
| SCHEMBL17882280 | 0.71 | RIPK1 (0.50) | RIPK1KDM4EALDH1A1 | |
| SCHEMBL13058298 | 0.70 | BCHE (0.50) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197098-B | Cell necrosis inhibitor | 北京生命科学研究所 | 2023-08-08 | — | — | CN | disclosed |
| CN-115197098-A | Cell necrosis inhibitor | 北京生命科学研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-107108467-B | Cell necrosis inhibitor | 北京生命科学研究所 | 2022-08-19 | — | — | CN | disclosed |