Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | FES | P07332 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.54 |
| ▸ | MARK3 | P27448 | 1/20 | 0.54 |
| ▸ | TYK2 | P29597 | 1/20 | 0.54 |
| ▸ | FLT4 | P35916 | 1/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882320 | 1.00 | RIPK1 (0.68) | RIPK1PKMKMT2AMAPTALDH1A1 | |
| SCHEMBL7756436 | 0.86 | RECQL (0.64) | PKMKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL13713518 | 0.86 | RIPK1 (0.54) | RIPK1PKMKMT2AMAPTALDH1A1 | |
| SCHEMBL15293597 | 0.82 | ALDH1A1 (0.58) | RIPK1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL9331928 | 0.82 | MAPT (0.59) | PKMKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL9331917 | 0.82 | MAPT (0.59) | PKMKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL20221145 | 0.81 | RIPK1 (0.71) | RIPK1MAPTALDH1A1LMNAHTT | |
| SCHEMBL13774770 | 0.81 | PKM (0.58) | PKMKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL1709321 | 0.81 | RIPK1 (1.00) | RIPK1MAPTALDH1A1LMNA | |
| SCHEMBL7663247 | 0.80 | RECQL (0.64) | PKMKMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197098-B | Cell necrosis inhibitor | 北京生命科学研究所 | 2023-08-08 | — | — | CN | disclosed |
| CN-115197098-A | Cell necrosis inhibitor | 北京生命科学研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-107108467-B | Cell necrosis inhibitor | 北京生命科学研究所 | 2022-08-19 | — | — | CN | disclosed |