SCHEMBL2991350

SCHEMBL2991350

CC(c1ccc(C(C)(C)C)cc1)C1CCCc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
HTT P42858 2/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
SIGMAR1 Q99720 1/20 0.40
TAOK1 Q7L7X3 1/20 0.40
TAOK3 Q9H2K8 1/20 0.40
IDO1 P14902 2/20 0.38
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
MAPK1 P28482 1/20 0.35
MAPK14 Q16539 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3000325 0.85 IDO1 (0.44) HTTALDH1A1IDO1
SCHEMBL29463951 0.85 IDO1 (0.44) HTTALDH1A1IDO1
SCHEMBL3296406 0.75 IDO1 (0.49) IDO1
SCHEMBL3000155 0.75 IDO1 (0.49) IDO1
Toluene SCHEMBL7619403 0.74 EPHX2 (0.39) ALDH1A1SIGMAR1
SCHEMBL10786594 0.74 ALDH1A1 (0.44) ALDH1A1IDO1
SCHEMBL15540606 0.72 IDO1 (0.50) IDO1
SCHEMBL4081534 0.72 IDO1 (0.46) IDO1
SCHEMBL13006752 0.72 IDO1 (0.50) IDO1
Hydrogen Peroxide SCHEMBL9456544 0.72 IDO1 (0.46) HTTMEN1ALDH1A1KMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
EP-0224259-B1 A WORKING FLUID FOR TRACTION DRIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-02-10 EP disclosed
US-4684754-A DECAHYDRONAPHTHALENE DERIVATIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-08-04 US disclosed
US-4609481-A DECALYLALKYLCYCLOHEXANE IDEMITSU KOSAN COMPANY LIMITED (JP) 1986-09-02 US disclosed
US-4525290-A Process for improving traction coefficient of traction drive fluid at high temperatures IDEMITSU KOSAN COMPANY LIMITED (JP) 1985-06-25 US disclosed