Toluene

Toluene

SCHEMBL7619403

CC(c1ccccc1)C1CCCc2ccccc21.Cc1ccccc1.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.39
ALDH1A1 P00352 1/20 0.37
SLC18A2 Q05940 1/20 0.37
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3000325 0.87 IDO1 (0.44) ALDH1A1
SCHEMBL29463951 0.87 IDO1 (0.44) ALDH1A1
SCHEMBL7619407 0.79 TAS1R3 (0.36) ALDH1A1
SCHEMBL11676122 0.74 EPHX2 (0.48) EPHX2SIGMAR1
SCHEMBL2991350 0.74 LMNA (0.47) ALDH1A1SIGMAR1
SCHEMBL5549328 0.72 IDO1 (0.44) ALDH1A1SIGMAR1
Hydrogen Peroxide SCHEMBL9456544 0.72 IDO1 (0.46) ALDH1A1
SCHEMBL3296406 0.71 IDO1 (0.49)
SCHEMBL3000155 0.71 IDO1 (0.49)
SCHEMBL23022884 0.71 ALDH1A1 (0.48) EPHX2ALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0980410-B1 THERMAL FLUID BLENDS CONTAINING 1,2,3,4-TETRAHYDRO(1-PHENYLETHYL)NAPHTHALENE DOW CHEMICAL CO (US) 2002-03-27 EP disclosed