Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913488 | 0.81 | CCR3 (0.45) | HTR1ADRD2LMNAHTR2CHTR3A | |
| SCHEMBL27228335 | 0.78 | LIPG (0.42) | KCNH2P2RY1HTR4CHRM4HTR2A | |
| SCHEMBL29913595 | 0.67 | MAPK1 (0.36) | NPY1ROPRL1KCNH2CHRM4DRD2 | |
| SCHEMBL22415720 | 0.65 | NISCH (0.35) | LMNA | |
| SCHEMBL27228377 | 0.65 | CACNA1I (0.50) | KCNH2HTR4HTR1ADRD2HTR2A | |
| SCHEMBL31016692 | 0.64 | HTR4 (0.47) | HTR4HTR2A | |
| SCHEMBL28081867 | 0.63 | KDM4E (0.42) | — | |
| SCHEMBL29913465 | 0.63 | CHRM2 (0.47) | OPRL1HTR1ADRD2HTR2CHTR3A | |
| SCHEMBL18233563 | 0.63 | CCR3 (0.67) | KCNH2 | |
| SCHEMBL22477406 | 0.62 | CHRM5 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4305029-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022189392-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-b]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-09-15 | — | — | WO | disclosed |