SCHEMBL29913855

SCHEMBL29913855

Cc1c(C(=O)Nc2nnco2)ccc(C(F)(F)F)c1[S@@+](C)[O-]

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
CSNK2A1 P68400 1/20 0.34
CSNK2A3 Q8NEV1 1/20 0.34
LMNA P02545 3/20 0.33
HTT P42858 2/20 0.33
ADCY8 P40145 2/20 0.31
ADCY1 Q08828 2/20 0.31
TMPRSS4 Q9NRS4 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
SORT1 Q99523 3/20 0.31
RAB9A P51151 3/20 0.31
TP53 P04637 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MAPT P10636 1/20 0.31
NPC1 O15118 2/20 0.30
GAA P10253 1/20 0.30
ALOX5 P09917 1/20 0.30
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29115244 1.00 CSNK2A2 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL30614217 1.00 CSNK2A2 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL30614203 0.88 NOTUM (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL27003649 0.88 NOTUM (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL30614196 0.88 NOTUM (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL19977985 0.83 KDM4E (0.40) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL19283622 0.82 ADCY8 (0.37) LMNAHTTADCY8ADCY1TMPRSS4
SCHEMBL31579375 0.80 CSNK2A2 (0.35) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL31579318 0.79 LMNA (0.35) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL27003672 0.77 KDM4E (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4305025-A1 CHIRAL N-(1,3,4-OXADIAZOLE-2-YL)PHENYL CARBOXYLIC ACID AMIDES AND THEIR USE AS HERBICIDES Bayer Aktiengesellschaft (DE) 2024-01-17 EP disclosed
CN-116964040-A Chiral N- (1, 3, 4-oxadiazol-2-yl) phenylcarboxylic acid amides and their use as herbicides 拜耳公司 2023-10-27 CN disclosed
WO-2022189495-A1 CHIRAL N-(1,3,4-OXADIAZOLE-2-YL)PHENYL CARBOXYLIC ACID AMIDES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2022-09-15 WO disclosed