SCHEMBL31579375

SCHEMBL31579375

CSc1c(C(F)(F)F)ccc(C(=O)Nc2nnco2)c1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
CSNK2A1 P68400 1/20 0.35
CSNK2A3 Q8NEV1 1/20 0.35
TMPRSS4 Q9NRS4 1/20 0.34
SORT1 Q99523 6/20 0.34
HTT P42858 3/20 0.34
LMNA P02545 2/20 0.34
ADCY8 P40145 2/20 0.32
ADCY1 Q08828 2/20 0.32
RXFP1 Q9HBX9 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
RAB9A P51151 3/20 0.32
TP53 P04637 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 1/20 0.32
PDE4B Q07343 1/20 0.31
NPC1 O15118 2/20 0.31
GMNN O75496 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17413646 0.83 KDM4E (0.41) CSNK2A2CSNK2BCSNK2A1CSNK2A3TMPRSS4
SCHEMBL15786297 0.82 SORT1 (0.38) CSNK2A2CSNK2BCSNK2A1CSNK2A3TMPRSS4
SCHEMBL19283615 0.81 TMPRSS4 (0.38) TMPRSS4SORT1HTTLMNAADCY8
SCHEMBL31579318 0.81 LMNA (0.35) CSNK2A2CSNK2BCSNK2A1CSNK2A3TMPRSS4
SCHEMBL30614217 0.80 CSNK2A2 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3TMPRSS4
SCHEMBL29913855 0.80 CSNK2A2 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3TMPRSS4
SCHEMBL29115244 0.80 CSNK2A2 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3TMPRSS4
SCHEMBL27003672 0.79 KDM4E (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3TMPRSS4
SCHEMBL17409841 0.76 NPC1 (0.42) TMPRSS4SORT1HTTRXFP1RAB9A
SCHEMBL25007892 0.75 CSNK2A2 (0.37) CSNK2A2CSNK2BCSNK2A1CSNK2A3TMPRSS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025103939-A1 SULFONIMIDOYL BENZAMIDES WITH HERBICIDAL ACTION BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed