Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | VEGFA | P15692 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11932534 | 0.88 | FAAH (0.57) | HRH3VEGFAEGLN1FAAHCHRM2 | |
| SCHEMBL2194827 | 0.87 | KDM1A (0.57) | VEGFAEGLN1KDM1ACHRM2CHRM4 | |
| SCHEMBL4156092 | 0.84 | VEGFA (0.58) | HRH3VEGFAEGLN1KDM1ACHRM2 | |
| SCHEMBL32667348 | 0.83 | VEGFA (0.64) | HRH3VEGFAEGLN1KDM1ACHRM1 | |
| SCHEMBL1362969 | 0.81 | FAAH (0.49) | VEGFAEGLN1CRBNFAAHCHRM2 | |
| SCHEMBL21198803 | 0.80 | VEGFA (0.55) | HRH3VEGFAEGLN1CHRM2CHRM4 | |
| SCHEMBL2862442 | 0.80 | ALDH1A1 (0.60) | VEGFAEGLN1FAAHCHRM2CHRM4 | |
| SCHEMBL5570585 | 0.79 | VEGFA (0.50) | VEGFAEGLN1KDM1ACHRM2CHRM4 | |
| SCHEMBL4938599 | 0.79 | VEGFA (0.56) | HRH3VEGFAEGLN1KDM1ACHRM2 | |
| SCHEMBL5536182 | 0.79 | VEGFA (0.68) | VEGFAEGLN1KDM1AFAAHCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094300-B | Benzo-heteroaryl derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-09-16 | — | — | CN | disclosed |