SCHEMBL1362969

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24732680	0.94	PRMT6 (0.54)	GLSPRMT6TBK1CHRM2CHRM4
	SCHEMBL1362326	0.89	IDO1 (0.45)	GLSTBK1CHRM2CHRM1CHRM3
	SCHEMBL21198803	0.86	VEGFA (0.55)	GLSPRMT6CHRM2CHRM4CHRM1
	SCHEMBL4709921	0.85	GLS (0.52)	GLSTBK1CHRM2CHRM4CHRM1
	SCHEMBL1632572	0.84	FAAH (0.53)	FAAHGLSTBK1CHRM4CHRM3
	SCHEMBL266762	0.84	GLS (0.51)	GLSTBK1CHRM2CHRM4CHRM1
	SCHEMBL27621253	0.83	NR1H2 (0.46)	CHRM2CHRM4CHRM1CHRM3CRBN
	SCHEMBL8540779	0.83	ALDH1A1 (0.63)	FAAHGLSCHRM2CHRM3KDM4E
	SCHEMBL4837787	0.83	GLS (0.54)	GLSTBK1CHRM2CHRM4CHRM1
	SCHEMBL2194827	0.83	KDM1A (0.57)	GLSCHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.