SCHEMBL29914775

SCHEMBL29914775

CN(C)Cc1cc(B2OC(C)(C)C(C)(C)O2)ccc1C1CCOCC1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.36
LPL P06858 13/20 0.36
MAP4K1 Q92918 1/20 0.35
ROCK1 Q13464 1/20 0.33
HIF1A Q16665 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
F11 P03951 1/20 0.32
HTR1D P28221 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22820460 1.00 LIPG (0.36) LIPGLPLMAP4K1ROCK1HIF1A
Hydrochloric Acid SCHEMBL27159968 0.99 LIPG (0.35) LIPGLPLMAP4K1ROCK1HIF1A
SCHEMBL27159651 0.89 LIPG (0.36) LIPGLPLROCK1HIF1AF11
SCHEMBL27159697 0.84 CNR1 (0.33) LIPGLPLROCK1HIF1A
SCHEMBL27160169 0.81 LIPG (0.39) LIPGLPLROCK1HIF1AF11
SCHEMBL27159737 0.81 OPRL1 (0.39) LIPGLPLHIF1A
SCHEMBL27159666 0.81 RORC (0.35) HIF1A
SCHEMBL29914872 0.81 LPL (0.33) LIPGLPLROCK1HIF1AATM
SCHEMBL29914723 0.81 LPL (0.33) LIPGLPLROCK1HIF1AKDM4E
SCHEMBL27159919 0.81 LPL (0.33) LIPGLPLROCK1HIF1AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4330246-A1 HALO-SUBSTITUTED AMINO AZA-HETEROARYL COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) Ontario Institute for Cancer Research (OICR) (CA) 2024-03-06 EP disclosed
WO-2022226666-A1 SUBSTITUTED AMINO AZA-HETEROARYL COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) 2022-11-03 WO disclosed
WO-2022226665-A1 HALO-SUBSTITUTED AMINO AZA-HETEROARYL COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) 2022-11-03 WO disclosed
WO-2022226668-A1 HALO-SUBSTITUTED AMINO PYRIDINE COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) 2022-11-03 WO disclosed