Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189733 | 0.79 | TDP1 (0.34) | ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL28129418 | 0.78 | BCL9 (0.40) | GAABCL9CTNNB1ALDH1A1MGLL | |
| SCHEMBL6833631 | 0.77 | TDP1 (0.33) | MAPTNPSR1 | |
| SCHEMBL4891567 | 0.77 | TDP1 (0.33) | MAPTNPSR1 | |
| SCHEMBL7959193 | 0.75 | GAA (0.43) | GAABCL9CTNNB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4391556 | 0.75 | GAA (0.43) | GAABCL9CTNNB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7267095 | 0.75 | POLB (0.45) | MAPT | |
| SCHEMBL7326761 | 0.75 | MAPT (0.35) | GAAALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL5873703 | 0.73 | — | — | |
| SCHEMBL9320151 | 0.72 | TPSAB1 (0.43) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3118211-B1 | AMIDE COMPOUNDS, METHODS FOR PREPARATION, AND USE THEREOF AS AGENTS FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY RNA-AND/OR DNA-CONTAINING VIRUSES AND CONCOMITANT DISEASES | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2022-10-12 | — | — | EP | disclosed |