SCHEMBL4891567

SCHEMBL4891567

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.33
POLB P06746 3/20 0.33
MAPT P10636 2/20 0.33
TPSAB1 Q15661 2/20 0.31
TPSD1 Q9BZJ3 2/20 0.31
TPSG1 Q9NRR2 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
SSTR4 P31391 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6833631 1.00 TDP1 (0.33) TDP1POLBMAPTTPSAB1TPSD1
Imidazole SCHEMBL4579994 0.92
SCHEMBL9320151 0.88 TPSAB1 (0.43) TDP1POLBMAPTTPSAB1TPSD1
SCHEMBL8189733 0.88 TDP1 (0.34) TDP1POLBMAPTNPSR1ATM
SCHEMBL26923344 0.87 HTR2C (0.34) MAPT
SCHEMBL29683397 0.87 HTR2C (0.34) MAPT
SCHEMBL29520467 0.85 MMP13 (0.32) TDP1POLBMAPT
SCHEMBL2133987 0.83 MDM2 (0.38) TPSAB1TPSD1TPSG1
SCHEMBL22610140 0.83 MDM2 (0.38) TPSAB1TPSD1TPSG1
SCHEMBL7267095 0.83 POLB (0.45) TDP1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
CN-118930602-A Method for performing terminal allylation modification on natural amino acid or polypeptide 南京工业大学 2024-11-12 CN disclosed
CN-118725014-A Mitochondrial targeting peptides 隐形生物治疗公司 2024-10-01 CN disclosed
CN-118702767-A Mitochondrial targeting peptides 隐形生物治疗公司 2024-09-27 CN disclosed
CN-118702766-A Mitochondrial targeting peptides 隐形生物治疗公司 2024-09-27 CN disclosed
CN-111954539-B Mitochondrial targeting peptides 隐形生物治疗公司 2024-06-21 CN disclosed
US-20240059734-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2024-02-22 US disclosed
WO-2023236573-A1 METHOD FOR PREPARING HIGH-SPECIFIC-VOLUME LOW-VOLTAGE ELECTRODE FOIL FOR AUTOMOTIVE ELECTRONICS 南通海星电子股份有限公司 2023-12-14 WO disclosed
US-11795196-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2023-10-24 US disclosed
US-20030077334-A1 Methods for production of the oxidized glutathione composite with cis-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanism for normal and transformed cells KOZHEMYAKIN LEONID A (RU) 2003-04-24 US disclosed
EP-0873123-B1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIV PITTSBURGH (US) 2003-04-09 EP disclosed
US-20020193596-A1 Inhibitors of protein isoprenyl transferases UNIVERSITY OF PITTSBURGH (US) 2002-12-19 US disclosed
US-20020016288-A1 Methods for production of the oxidized glutathione composite with cis-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells KOZHEMYAKIN LEONID A (RU) 2002-02-07 US disclosed
US-6312734-B1 FORMING AN OXIDIZED GLUTATIONE COMPLEX WITH PLATINUM OR PALLADIUM NOVELOS THERAPEUTICS, INC. 2001-11-06 US disclosed
EP-1131340-A2 HEXAPEPTIDE WITH THE STABILIZED DISULFIDE BOND AND DERIVATIVES THEREOF REGULATING METABOLISM, PROLIFERATION, DIFFERENTIATION AND APOPTOSIS Novelos Therapeutics, Inc. (US) 2001-09-12 EP disclosed
WO-2000031120-A2 HEXAPEPTIDE WITH THE STABILIZED DISULFIDE BOND AND DERIVATIVES THEREOF REGULATING METABOLISM, PROLIFERATION, DIFFERENTIATION AND APOPTOSIS NOVELOS THERAPEUTICS, INC. (US) 2000-06-02 WO disclosed
US-4859654-A Homocyclostatine and cyclostatine containing polypeptides as antihypertensive agents PFIZER INC. (US) 1989-08-22 US disclosed
US-4818748-A HYPOTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1989-04-04 US disclosed
EP-0236874-A2 Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes BAYER AG (DE) 1987-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193596-A1 Inhibitors of protein isoprenyl transferases LANCL1, FNTB, DHCR7 TDP1 3740/4885POLB 2803/4885MAPT 4674/4885
US-20020016288-A1 Methods for production of the oxidized glutathione composite with cis-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells GPX4, GPX1, GSR TDP1 3397/4885POLB 671/4885MAPT 3853/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 TDP1 720/4885POLB 948/4885MAPT 4146/4885
US-20030077334-A1 Methods for production of the oxidized glutathione composite with cis-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanism for normal and transformed cells GPX4, GPX1, GSR TDP1 3407/4885POLB 694/4885MAPT 3830/4885
US-11795196-B2 Mitochondria-targeting peptides HSPE1, TFAM, TNNI3 TDP1 2124/4885POLB 1250/4885MAPT 4363/4885
US-20240059734-A1 MITOCHONDRIA-TARGETING PEPTIDES HSPE1, TFAM, TNNI3 TDP1 2124/4885POLB 1250/4885MAPT 4363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.