Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416816 | 0.85 | RAB9A (0.43) | HTR2AMAPTL3MBTL1 | |
| SCHEMBL7782152 | 0.83 | SLC1A3 (0.37) | KMT2APKMMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7782151 | 0.83 | SLC1A3 (0.37) | KMT2APKMMAPTALDH1A1L3MBTL1 | |
| Histidine SCHEMBL8315963 | 0.80 | ITGB3 (0.46) | KMT2APKMHTR2ALMNAMAPT | |
| SCHEMBL1171906 | 0.80 | ITGB3 (0.46) | KMT2APKMHTR2ALMNAMAPT | |
| Histidine SCHEMBL8316688 | 0.80 | ITGB3 (0.46) | KMT2APKMHTR2ALMNAMAPT | |
| SCHEMBL29576680 | 0.79 | MEN1 (0.43) | KMT2AGAALMNAMAPTALDH1A1 | |
| SCHEMBL27515997 | 0.78 | KMT2A (0.46) | KMT2AMGLLLMNAMAPTALDH1A1 | |
| SCHEMBL29914784 | 0.78 | GAA (0.40) | BCL9CTNNB1MGLLGAAHTR2A | |
| SCHEMBL1653019 | 0.77 | ALDH1A1 (0.38) | KMT2ALMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459144-A | Amide compounds, methods of production and uses thereof | 制药有限责任公司 | 2017-02-22 | — | — | CN | disclosed |