Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640571 | 1.00 | TSHR (0.52) | TSHRTHRBALDH1A1NOS1NOS3 | |
| SCHEMBL13525584 | 0.86 | NOS1 (0.34) | TSHRNOS1NOS3NOS2SLC7A5 | |
| SCHEMBL2519906 | 0.80 | GAA (0.37) | NOS1NOS3NOS2SLC7A5LTA4H | |
| SCHEMBL1231993 | 0.78 | TSHR (0.59) | TSHRTHRBALDH1A1NOS1NOS3 | |
| SCHEMBL27887489 | 0.78 | TSHR (0.59) | TSHRTHRBALDH1A1NOS1NOS3 | |
| SCHEMBL10187395 | 0.78 | TSHR (0.59) | TSHRTHRBALDH1A1NOS1NOS3 | |
| SCHEMBL17997774 | 0.78 | TSHR (0.59) | TSHRTHRBALDH1A1NOS1NOS3 | |
| SCHEMBL1810183 | 0.77 | TSHR (0.75) | TSHRTHRBALDH1A1 | |
| SCHEMBL28815245 | 0.77 | NOS1 (0.35) | TSHRNOS1NOS3NOS2SLC7A5 | |
| SCHEMBL181537 | 0.77 | TSHR (0.57) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220325072-A1 | ZWITTERIONIC CROSSLINKERS, HYDROGELS COMPRISING ZWITTERIONIC CROSSLINKERS, AND METHODS FOR MAKING AND USING | UNIVERSITY OF IDAHO | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220325072-A1 | ZWITTERIONIC CROSSLINKERS, HYDROGELS COMPRISING ZWITTERIONIC CROSSLINKERS, AND METHODS FOR MAKING AND USING | ASS1, GFER, ASIC1 | TSHR 1073/4885THRB 2043/4885ALDH1A1 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.