Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.68 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.68 |
| ▸ | F7 | P08709 | 1/20 | 0.62 |
| ▸ | F3 | P13726 | 1/20 | 0.62 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.62 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.62 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.62 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.62 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.62 |
| ▸ | HPGDS | O60760 | 1/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.52 |
| ▸ | ATR | Q13535 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22578364 | 1.00 | MKNK1 (0.68) | MKNK1MKNK2F7F3SARM1 | |
| SCHEMBL30201337 | 0.85 | LDHA (0.74) | MKNK1MKNK2CYP2A6CYP3A4LDHA | |
| SCHEMBL3203644 | 0.85 | LDHA (0.74) | MKNK1MKNK2CYP2A6CYP3A4LDHA | |
| SCHEMBL29586559 | 0.84 | LDHA (0.73) | MKNK1MKNK2HPGDSFYNCHEK2 | |
| SCHEMBL1246554 | 0.84 | LDHA (0.73) | MKNK1MKNK2HPGDSFYNCHEK2 | |
| SCHEMBL14355076 | 0.83 | HPGDS (0.56) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL30144078 | 0.83 | MKNK1 (0.67) | MKNK1MKNK2F7F3SARM1 | |
| Hydrochloric Acid SCHEMBL5010814 | 0.83 | LDHA (0.71) | MKNK1MKNK2HPGDSFYNCHEK2 | |
| SCHEMBL1758258 | 0.81 | LDHA (0.69) | MKNK1MKNK2HPGDSFYNCHEK2 | |
| SCHEMBL606654 | 0.81 | MKNK1 (1.00) | MKNK1MKNK2F7F3SARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3798214-B1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2022-09-14 | — | — | EP | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |
| EP-4041714-B1 | BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH INC (US) | 2023-12-13 | — | — | EP | disclosed |