Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | SDHB | P21912 | 1/20 | 0.50 |
| ▸ | KLRK1 | P26718 | 3/20 | 0.49 |
| ▸ | MICA | Q29983 | 3/20 | 0.49 |
| ▸ | RAET1L | Q5VY80 | 3/20 | 0.49 |
| ▸ | APOB | P04114 | 3/20 | 0.49 |
| ▸ | MTTP | P55157 | 3/20 | 0.49 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645473 | 1.00 | SLC6A3 (0.69) | SLC6A3SLC6A4SLC6A2CFTRGAA | |
| SCHEMBL31676838 | 0.89 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2CFTRSDHB | |
| SCHEMBL23354524 | 0.89 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2CFTRSDHB | |
| SCHEMBL29917415 | 0.87 | SLC6A3 (0.52) | SLC6A3SLC6A4SLC6A2CFTRGAA | |
| SCHEMBL23354401 | 0.87 | SLC6A3 (0.64) | SLC6A3SLC6A4SLC6A2CFTRSDHB | |
| SCHEMBL29979219 | 0.87 | SLC6A3 (0.64) | SLC6A3SLC6A4SLC6A2CFTRSDHB | |
| SCHEMBL29979412 | 0.86 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2CFTRROCK2 | |
| SCHEMBL23354290 | 0.86 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2CFTRROCK2 | |
| SCHEMBL23354286 | 0.85 | SLC6A3 (0.62) | SLC6A3SLC6A4SLC6A2GAASDHB | |
| SCHEMBL29979533 | 0.85 | SLC6A3 (0.62) | SLC6A3SLC6A4SLC6A2GAASDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398120-B2 | Substituted hydantoinamides as ADAMTS7 antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2025-08-26 | — | — | US | disclosed |
| EP-4058448-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2022-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12398120-B2 | Substituted hydantoinamides as ADAMTS7 antagonists | ADAMTS7, MMP7, ADAM17 | SLC6A3 1469/4885SLC6A4 1821/4885SLC6A2 3380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.