Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17648477 | 1.00 | NNMT (0.38) | NNMTMITFALDH1A1LMNAMAPT | |
| SCHEMBL19121101 | 0.91 | IKBKB (0.35) | NNMTMITFALDH1A1LMNAMAPT | |
| SCHEMBL29917990 | 0.88 | PDE4B (0.35) | NNMTLMNAF10CRHR1CDK8 | |
| SCHEMBL17646572 | 0.88 | MEN1 (0.38) | ALDH1A1LMNASMN1; SMN2CRHR1KDM4E | |
| SCHEMBL20350431 | 0.86 | MAPT (0.37) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23182985 | 0.85 | F10 (0.38) | LMNASMN1; SMN2F10CRHR1NPC1 | |
| SCHEMBL29917027 | 0.79 | CRHR1 (0.34) | ALDH1A1CDK5CRHR1IKBKBKDM4E | |
| SCHEMBL29917505 | 0.79 | FLT1 (0.47) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17648576 | 0.79 | FLT1 (0.47) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19440563 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3798214-B1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2022-09-14 | — | — | EP | claimed |