Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384125 | 0.87 | HDAC1 (0.54) | HDAC1MAP4K4GPR119NR1H2NR1H3 | |
| SCHEMBL29919690 | 0.84 | ALDH1A1 (0.47) | HDAC1MAP4K4GPR119NR1H2NR1H3 | |
| SCHEMBL25703562 | 0.83 | SMARCA2 (0.51) | MAP4K4GPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL13999776 | 0.78 | HDAC1 (0.49) | HDAC1MAP4K4GPR119NR1H2NR1H3 | |
| SCHEMBL3621405 | 0.78 | HDAC1 (0.52) | HDAC1MAP4K4GPR119NR1H2NR1H3 | |
| SCHEMBL24719091 | 0.78 | DRD2 (0.50) | HDAC1MAP4K4GPR119SUV39H2 | |
| SCHEMBL28520979 | 0.78 | MAP4K4 (0.49) | HDAC1MAP4K4GPR119NR1H2NR1H3 | |
| SCHEMBL29799403 | 0.78 | DRD2 (0.50) | HDAC1MAP4K4GPR119SUV39H2 | |
| SCHEMBL28600264 | 0.78 | DRD2 (0.50) | HDAC1MAP4K4GPR119SUV39H2 | |
| SCHEMBL13039967 | 0.78 | HDAC1 (0.47) | HDAC1MAP4K4GPR119NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220289719-A1 | HETEROCYCLIC COMPOUNDS AS MNK INHIBITORS | NANJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2022-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220289719-A1 | HETEROCYCLIC COMPOUNDS AS MNK INHIBITORS | NIM1K, MAP3K1, MAPKAPK2 | HDAC1 371/4885MAP4K4 36/4885GPR119 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.