Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920680 | 0.79 | AKR1B1 (0.37) | AKR1B1RIPK1LMNA | |
| SCHEMBL12258493 | 0.69 | AKR1B1 (0.47) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL29920342 | 0.67 | AKR1B1 (0.36) | AKR1B1RIPK1LMNA | |
| SCHEMBL31372173 | 0.67 | AKR1B1 (0.44) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL12234883 | 0.65 | AKR1B1 (0.41) | AKR1B1RIPK1AKR1B10MAPTAKR1A1 | |
| SCHEMBL15236792 | 0.63 | AKR1B1 (0.39) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL9824148 | 0.62 | AKR1B1 (0.59) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL7867894 | 0.61 | AKR1B10 (0.80) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL12620675 | 0.61 | AKR1B10 (0.80) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL17729307 | 0.61 | AKR1B1 (0.55) | AKR1B1AKR1B10MAPTAKR1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |