Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12258493 | 0.80 | AKR1B1 (0.47) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL19889348 | 0.80 | LMNA (0.46) | MAPTMAP3K14HTR2CBACE1 | |
| SCHEMBL19889242 | 0.80 | MAP3K14 (0.39) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL12234883 | 0.76 | AKR1B1 (0.41) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL19889349 | 0.76 | ALDH1A1 (0.46) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL21134901 | 0.76 | PTGS1 (0.36) | MAPTMAP3K14KMT2A | |
| SCHEMBL28284856 | 0.75 | ITGB2 (0.46) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL1827688 | 0.74 | AKR1B1 (0.39) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL15236792 | 0.74 | AKR1B1 (0.39) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL12620675 | 0.72 | AKR1B10 (0.80) | AKR1B1AKR1B10MAPTAKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025036382-A1 | SULFONAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海复宏汉霖生物医药有限公司 | 2025-02-20 | — | — | WO | disclosed |