Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294370 | 0.93 | DNM1 (0.69) | DNM1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL29602421 | 0.91 | DNM1 (0.67) | DNM1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL29372083 | 0.88 | DNM1 (0.62) | DNM1KDM4CKDM4APHF8KDM2A | |
| Lactic Acid SCHEMBL3863099 | 0.87 | DNM1 (0.80) | DNM1FAAHNOD1 | |
| Lactic Acid SCHEMBL428727 | 0.87 | DNM1 (0.80) | DNM1FAAHNOD1 | |
| Lactic Acid SCHEMBL3336829 | 0.87 | DNM1 (0.80) | DNM1FAAHNOD1 | |
| Lactic Acid SCHEMBL128277 | 0.87 | DNM1 (0.80) | DNM1FAAHNOD1 | |
| SCHEMBL3288351 | 0.85 | DNM1 (0.68) | DNM1KDM4CKDM4APHF8KDM2A | |
| Lactic Acid SCHEMBL4093963 | 0.82 | PAOX (0.53) | DNM1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL32685811 | 0.82 | DNM1 (0.54) | DNM1KDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447640-B2 | Encapsulated materials with improved properties | SUN CHEMICAL CORPORATION (US) | 2022-09-20 | — | — | US | disclosed |