Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL8518547 | 0.94 | PAOX (0.48) | PAOXKDM4CKDM4APHF8KDM2A | |
| SCHEMBL19516596 | 0.87 | TDP1 (0.52) | PAOXKDM4CKDM4APHF8KDM2A | |
| Lactic Acid SCHEMBL8519748 | 0.86 | PAOX (0.54) | PAOXKDM4ETDP1ALDH1A1DNM1 | |
| Hydrochloric Acid SCHEMBL31278439 | 0.85 | PAOX (0.50) | PAOXKDM4CKDM4APHF8KDM2A | |
| Lactic Acid SCHEMBL8518756 | 0.84 | PAOX (0.53) | PAOXKDM4ETDP1ALDH1A1DNM1 | |
| Lactic Acid SCHEMBL29920920 | 0.82 | DNM1 (0.60) | PAOXKDM4CKDM4APHF8KDM2A | |
| SCHEMBL27435358 | 0.79 | PAOX (0.47) | PAOXKDM4CKDM4APHF8KDM2A | |
| SCHEMBL30463700 | 0.79 | CYP2C19 (0.50) | PAOXKDM4CKDM4APHF8KDM2A | |
| SCHEMBL30463704 | 0.79 | CYP2C19 (0.50) | PAOXKDM4CKDM4APHF8KDM2A | |
| SCHEMBL30463701 | 0.79 | CYP2C19 (0.50) | PAOXKDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485154-B2 | Textile treatment compositions including a sublimable material | GIVAUDAN SA (CH) | 2009-02-03 | — | — | US | disclosed |
| EP-1556469-B1 | TEXTILE TREATMENT COMPOSITIONS INCLUDING A SUBLIMABLE MATERIAL | GIVAUDAN SA (CH) | 2007-12-05 | — | — | EP | disclosed |
| US-20060010933-A1 | Textile treatment compositions including a sublimable material | GIVAUDAN SA (CH) | 2006-01-19 | — | — | US | disclosed |
| EP-1556469-A1 | TEXTILE TREATMENT COMPOSITIONS INCLUDING A SUBLIMABLE MATERIAL | Givaudan SA (CH) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037964-A1 | TEXTILE TREATMENT COMPOSITIONS INCLUDING A SUBLIMABLE MATERIAL | GIVAUDAN SA (CH) | 2004-05-06 | — | — | WO | disclosed |