SCHEMBL2992142

SCHEMBL2992142

[CH2]COC(=O)c1ccsc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
LCK P06239 1/20 0.50
FYN P06241 1/20 0.50
DAO P14920 1/20 0.50
HDAC1 Q13547 1/20 0.46
HPGD P15428 2/20 0.40
HSD11B1 P28845 1/20 0.39
ELANE P08246 5/20 0.38
GPR52 Q9Y2T5 1/20 0.36
KCNK3 O14649 1/20 0.35
KCNK9 Q9NPC2 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
PLAU P00749 1/20 0.35
HSD17B10 Q99714 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1183367 0.84 CES2 (0.56) CES2CES1LCKFYNDAO
SCHEMBL827404 0.81 ELANE (0.53) CES2CES1LCKFYNDAO
SCHEMBL27343064 0.80 CYP3A4 (0.51) CES2CES1LCKFYNDAO
Hydrochloric Acid SCHEMBL30166750 0.79 ELANE (0.52) CES2CES1LCKFYNDAO
SCHEMBL9497679 0.78 LMNA (0.58) CES2CES1LCKFYNDAO
SCHEMBL7254758 0.78 CES2 (0.48) CES2CES1LCKFYNDAO
SCHEMBL6973487 0.78
SCHEMBL7648686 0.77 CES2 (0.62) CES2CES1LCKFYNDAO
SCHEMBL390383 0.77 CES2 (0.47) CES2CES1LCKFYNDAO
SCHEMBL29967144 0.77 CES2 (0.47) CES2CES1LCKFYNDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100172011-A1 SEMI-ELECTROACTIVE MATERIAL CONTAINING ORGANIC COMPOUNDS HAVING POSITIVE OR NEGATIVE REDOX ACTIVITY, PROCESS AND KIT FOR MANUFACTURING THIS MATERIAL, ELECTRICALLY CONTROLLABLE DEVICE AND GLAZING UNITS USING SUCH A SEMI-ELECTROACTIVE MATERIAL SAINT-GOBAIN GLASS FRANCE (FR) 2010-07-08 US claimed