SCHEMBL827404

SCHEMBL827404

CCOC(=O)c1ccsc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.53
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAOA P21397 1/20 0.52
HSD17B10 Q99714 2/20 0.50
HPGD P15428 2/20 0.50
LCK P06239 1/20 0.50
FYN P06241 1/20 0.50
DAO P14920 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30166750 0.98 ELANE (0.52) ELANECA12CA1CA2CA7
SCHEMBL9497679 0.85 LMNA (0.58) ELANEESR1CES2CES1LMNA
SCHEMBL1183367 0.84 CES2 (0.56) ELANEESR1ESR2CES2CES1
SCHEMBL9494666 0.82 ESR1 (0.58) ELANEESR1LMNACYP1A2CYP3A4
SCHEMBL18734776 0.81 CES2 (0.48) ELANECES2CES1CYP1A2HSD17B10
SCHEMBL3961016 0.81 CES2 (0.59) ELANECES2CES1CYP1A2HSD17B10
SCHEMBL6705545 0.81 MAPT (0.55) CA12CA1CA2CA7CA9
SCHEMBL9499078 0.81 ALDH1A1 (0.56) ESR1LMNACYP1A2CYP3A4MAPT
SCHEMBL2992142 0.81 CES2 (0.52) ELANECA1CA2CES2CES1
SCHEMBL29967144 0.80 CES2 (0.47) ELANECA1CA2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113735842-B 1,2, 4-triazole Schiff base thioether derivatives, and preparation method and application thereof 河北农业大学 2023-01-31 CN claimed
CN-108707222-A Electroluminescent polymer and the preparation method and application thereof of the one kind based on anthracene derivant 华南理工大学 2018-10-26 CN claimed
CN-108359443-A A kind of electroluminescent material and the preparation method and application thereof based on anthracene derivant 华南理工大学 2018-08-03 CN claimed
EP-2928561-A1 METHOD FOR TREATING A DISEASE ASSOCIATED WITH SOLUBLE, OLIGOMERIC SPECIES OF AMYLOID BETA 1-42 Acumen Pharmaceuticals, Inc. (US) 2015-10-14 EP claimed
WO-2014089149-A1 METHOD FOR TREATING A DISEASE ASSOCIATED WITH SOLUBLE, OLIGOMERIC SPECIES OF AMYLOID BETA 1-42 ACUMEN PHARMACEUTICALS, INC. (US) 2014-06-12 WO claimed
WO-2009124086-A2 ANTIBACTERIAL DRUG FOR TREATMENT OF STAPHYLOCOCCUS AUREUS AND OTHER GRAM-POSITIVE BACTERIAL INFECTIONS SIGA TECHNOLOGIES, INC. (US) 2009-10-08 WO claimed
EP-1492783-A1 4,5,6,7-TRETRAHYDROBENZO(B) THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS Axxima Pharmaceuticals AG (DE) 2005-01-05 EP claimed
WO-2003084947-A1 4,5,6,7-TRETRAHYDROBENZO[B] THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS AXXIMA PHARMACEUTICALS AG (DE) 2003-10-16 WO claimed
US-4634687-A COCATALYST FOR COORDINATION CATALYST TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1987-01-06 US claimed
CN-119968081-A Perovskite precursor solution, perovskite film, and preparation methods and applications thereof 德沪涂膜设备(苏州)有限公司 2025-05-09 CN disclosed
CN-119431394-A Pyridazinone derivatives and medical application thereof 杭州百新生物医药科技有限公司 2025-02-14 CN disclosed
CN-118619968-A Dihydrothienopyrimidino pyrido indol-4-one derivative and application thereof 新疆工程学院 2024-09-10 CN disclosed
US-12030879-B2 Sulfonyl acetamides as NLRP3 inhibitors INFLAZOME LIMITED (IE) 2024-07-09 US disclosed
US-12011444-B2 N-substituted indole derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-18 US disclosed
EP-0173472-A2 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-03-05 EP disclosed
EP-0173470-A2 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-03-05 EP disclosed
EP-0171155-A1 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-02-12 EP disclosed
EP-0171200-A2 Catalyst component for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-02-12 EP disclosed
US-4525555-A TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS NIPPON OIL COMPANY, LIMITED (JP) 1985-06-25 US disclosed
EP-0136163-A2 Process for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-04-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030879-B2 Sulfonyl acetamides as NLRP3 inhibitors NLRP3, NOD1, NLRP1 ELANE 3428/4885CA12 3218/4885CA1 1690/4885
US-12011444-B2 N-substituted indole derivatives as PGE2 receptor modulators PTGER1, PTGER4, PTGER2 ELANE 2389/4885CA12 4750/4885CA1 4424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.