Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403643 | 0.90 | GAA (0.72) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7623605 | 0.89 | GAA (0.70) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9648251 | 0.85 | GAA (0.66) | GAAALDH1A1KDM4EMAPTHPGD | |
| Dimethyl Phthalate SCHEMBL28028655 | 0.85 | GAA (0.66) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9398149 | 0.85 | GAA (0.66) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30311840 | 0.84 | MAPT (0.48) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL26054237 | 0.84 | MAPT (0.48) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL10289753 | 0.82 | GAA (0.62) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9705197 | 0.81 | GAA (0.65) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL2926607 | 0.81 | GAA (0.70) | GAAALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |