SCHEMBL2926607

SCHEMBL2926607

COC(=O)c1ccc(N)cc1N

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.70
ALDH1A1 P00352 8/20 0.70
KDM4E B2RXH2 6/20 0.70
MAPT P10636 6/20 0.70
HSD17B10 Q99714 3/20 0.70
HPGD P15428 3/20 0.70
GLA P06280 2/20 0.70
CASP1 P29466 1/20 0.70
CASP7 P55210 1/20 0.70
ATM Q13315 1/20 0.70
ABL1 P00519 1/20 0.68
CFTR P13569 3/20 0.62
MAPK1 P28482 1/20 0.53
TSHR P16473 2/20 0.51
ALOX15 P16050 1/20 0.51
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400478 1.00 GAA (0.70) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL8717841 0.88 GAA (0.57) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL1403643 0.86 GAA (0.72) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL7623605 0.84 GAA (0.70) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL6168887 0.84 GAA (0.66) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL30660134 0.83 MAPT (0.48) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL29358 0.82 KDM4E (1.00) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL616715 0.82 GAA (1.00) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL4826905 0.82 ALDH1A1 (0.68) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL1129582 0.82 ALDH1A1 (0.68) GAAALDH1A1KDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108033891-A The synthetic method of 3- amino-4-methoxyl carbonyl aniline 武汉理工大学 2018-05-15 CN claimed
US-6805718-B2 USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME NOVOZYMES A/S (DK) 2004-10-19 US claimed
US-20030226215-A1 Enzymatic method for textile dying NOVOZYMES NORTH AMERICA, INC. (US) 2003-12-11 US claimed
WO-2003016615-A1 SINGLE BATH PROCESS FOR BLEACHING AND DYEING TEXTILES NOVOZYMES NORTH AMERICA, INC. (US) 2003-02-27 WO claimed
EP-1266068-A1 ENZYMATIC METHOD FOR TEXTILE DYEING Novozymes North America, Inc. (US) 2002-12-18 EP claimed
US-20010037532-A1 Enzymatic method for textile dyeing NOVOZYMES A/S (DK) 2001-11-08 US claimed
US-6296672-B1 PEROXIDASE, OXIDOREDUCTASE, LACCASE NOVOZYMES A/S PATENTS (DK) 2001-10-02 US claimed
WO-2001044563-A1 ENZYMATIC METHOD FOR TEXTILE DYEING NOVOZYMES NORTH AMERICA, INC. (US) 2001-06-21 WO claimed
US-4107151-A FROM POLYISOCYANATE, CHAIN POLYOL, AROMATIC DIAMINE, POLYOL OR AMINO ALCOHOL WITH URETHANE BOND IHARA CHEMICAL COMPANY CO., LTD. (JP) 1978-08-15 US claimed
US-4054556-A Polyurethanes cured with derivatives of 2,4-diamino-benzoic acid E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-10-18 US claimed
JP-63216820-A None JP disclosed
CN-113544184-B Composition for film formation, cured film, liquid crystal alignment film, and retardation film JSR株式会社 2024-05-14 CN disclosed
US-20230357164-A1 NOVEL QUINAZOLINE DERIVATIVE HAVING FLT3 INHIBITORY ACTIVITY, AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2023-11-09 US disclosed
US-20230359119-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-09 US disclosed
CN-109789378-B Composite semipermeable membrane and spiral separation membrane element 日东电工株式会社 2022-02-25 CN disclosed
EP-0109624-A2 Process for producing shaped articles made from polyurethane-polyurea which may be cellular BASF Aktiengesellschaft (DE) 1984-05-30 EP disclosed
US-4107151-A FROM POLYISOCYANATE, CHAIN POLYOL, AROMATIC DIAMINE, POLYOL OR AMINO ALCOHOL WITH URETHANE BOND IHARA CHEMICAL COMPANY CO., LTD. (JP) 1978-08-15 US disclosed
US-4054556-A Polyurethanes cured with derivatives of 2,4-diamino-benzoic acid E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-10-18 US disclosed
US-4039514-A SUBSTITUTED 2,4-DIAMINOBENZOIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-08-02 US disclosed
US-3953496-A ANTIPYRETICS, ANTI-ALLERGIC, ANTI-INFLAMMATORY AGENTS CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357164-A1 NOVEL QUINAZOLINE DERIVATIVE HAVING FLT3 INHIBITORY ACTIVITY, AND USE THEREOF FLT3, ABL1, MCL1 GAA 2989/4885ALDH1A1 3264/4885KDM4E 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.