SCHEMBL2992219

SCHEMBL2992219

COc1ccc(C(=O)c2cc3c(OC)cc(OC)cc3oc2=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.59
PKM P14618 1/20 0.59
KMT2A Q03164 1/20 0.59
ALDH1A1 P00352 5/20 0.57
KDM4E B2RXH2 3/20 0.57
NPC1 O15118 2/20 0.57
POLB P06746 2/20 0.57
RAB9A P51151 1/20 0.57
MAOB P27338 5/20 0.57
MAOA P21397 1/20 0.57
MAPT P10636 1/20 0.54
HTT P42858 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
HPGD P15428 3/20 0.51
GLA P06280 2/20 0.51
HSD17B10 Q99714 2/20 0.51
CYP3A4 P08684 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CNR2 P34972 2/20 0.49
SLC22A12 Q96S37 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19725943 0.93 ALDH1A1 (0.52) MEN1PKMKMT2AALDH1A1KDM4E
SCHEMBL52178 0.91 ALDH1A1 (0.66) MEN1PKMKMT2AALDH1A1KDM4E
SCHEMBL29968097 0.91 ALDH1A1 (0.66) MEN1PKMKMT2AALDH1A1KDM4E
SCHEMBL34468485 0.89 ALDH1A1 (0.49) MEN1PKMKMT2AALDH1A1KDM4E
SCHEMBL21284577 0.89 MEN1 (0.54) MEN1PKMKMT2AALDH1A1KDM4E
SCHEMBL15660448 0.89 ALDH1A1 (0.49) MEN1PKMKMT2AALDH1A1KDM4E
SCHEMBL51758 0.89 CYP3A4 (0.54) MEN1PKMKMT2AALDH1A1KDM4E
SCHEMBL29436270 0.89 ALDH1A1 (0.55) MEN1PKMKMT2AALDH1A1KDM4E
SCHEMBL556704 0.89 ALDH1A1 (0.55) MEN1PKMKMT2AALDH1A1KDM4E
SCHEMBL19184746 0.89 KDM4E (0.51) MEN1PKMKMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114502601-B Combination of photoinitiators and use thereof 意大利艾坚蒙树脂有限公司 2024-09-13 CN disclosed
EP-3593786-B1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL TOKUYAMA DENTAL CORP (JP) 2022-05-18 EP disclosed
CN-114502601-A Combination of photoinitiators and uses thereof 意大利艾坚蒙树脂有限公司 2022-05-13 CN disclosed
US-11273104-B2 Photocurable composition and dental restoration filling material TOKUYAMA DENTAL CORPORATION (JP) 2022-03-15 US disclosed
EP-3427716-B1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2021-11-24 EP disclosed
CN-108697586-B Photopolymerization initiator and photocurable composition 株式会社德山齿科 2021-07-06 CN disclosed
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2021-04-01 US disclosed
US-20200069534-A1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL TOKUYAMA DENTAL CORPORATION (JP) 2020-03-05 US disclosed
EP-3427716-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION Tokuyama Dental Corporation (JP) 2019-01-16 EP disclosed
US-20130071804-A1 Adhesive for Teeth-Straightening Members TOKUYAMA DENTAL CORPORATION (JP) 2013-03-21 US disclosed
EP-1249221-A1 DENTAL ADHESIVE COMPOSITION Tokuyama Dental Corporation (JP) 2002-10-16 EP disclosed
EP-0738928-B1 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORP (JP) 2001-06-20 EP disclosed
US-6133338-A TYPIFIED BY 6-METHACRYLOYLOXYHEXYL 2-THIOURACIL-5-CARBOXYLATE, A RADICAL-POLYMERIZABLE MONOMER, AND A POLYMERIZATION INITIATOR; DENTAL ADHESIVE; GOOD ADHESIVENESS TO NOBLE METALS AND ALLOYS THEREOF TOKUYAMA CORPORATION (JP) 2000-10-17 US disclosed
EP-0636939-B1 Photoinitiator compositions and photosensitive materials using the same HITACHI CHEMICAL CO LTD (JP) 1999-03-03 EP disclosed
EP-0896043-A1 Adhesive TOKUYAMA CORPORATION (JP) 1999-02-10 EP disclosed
US-5811218-A IMPROVED PHOTOSENSITIVITY FOR MATERIALS CONTAINING POLYAMIC ACID AND ADDITION POLYMERIZABLE COMPOUND USED FOR PATTERN FORMATION HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-09-22 US disclosed
US-5744511-A BLEND OF COUMARIN DYES, ACID GENERATOR AND ARYL BORATE TOKUYAMA CORPORATION (JP) 1998-04-28 US disclosed
EP-0738928-A2 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORPORATION (JP) 1996-10-23 EP disclosed
EP-0636939-A2 Photoinitiator compositions and photosensitive materials using the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-02-01 EP disclosed
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11273104-B2 Photocurable composition and dental restoration filling material H1-0, REV1, RER1 MEN1 1122/4885PKM 2123/4885KMT2A 3632/4885
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION INO80C, JAK2, PCNA MEN1 2856/4885PKM 1803/4885KMT2A 444/4885
US-20200069534-A1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL REV1, H1-0, RAD51 MEN1 1293/4885PKM 2263/4885KMT2A 3697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.