Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 15/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26733219 | 0.93 | KDM4E (0.50) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL618056 | 0.80 | KDM4E (0.65) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL30833732 | 0.79 | DGAT1 (0.58) | — | |
| SCHEMBL1173693 | 0.79 | DGAT1 (0.44) | KDM4EGLA | |
| SCHEMBL12490665 | 0.79 | HTT (0.45) | — | |
| SCHEMBL13427 | 0.79 | DGAT1 (0.58) | — | |
| SCHEMBL4441828 | 0.78 | KDM4E (0.63) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL24252313 | 0.77 | ALDH1A1 (0.47) | KDM4E | |
| SCHEMBL4841620 | 0.75 | CPS1 (0.52) | KDM4E | |
| SCHEMBL22823915 | 0.74 | HPGD (0.56) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |