Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | GALR3 | O60755 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260625 | 0.83 | CES2 (0.43) | HPGDCES2GALR3CYP1A2CYP2C9 | |
| SCHEMBL873620 | 0.81 | ALDH1A1 (0.42) | HPGDGAAMAPTALDH1A1KMT2A | |
| SCHEMBL1340593 | 0.78 | KDM4E (0.56) | HPGDCES2GALR3CYP1A2CYP2C9 | |
| SCHEMBL4122910 | 0.77 | CA12 (0.50) | MAPTALDH1A1NPSR1KMT2AMAOA | |
| SCHEMBL1857398 | 0.77 | KDM4E (0.54) | MAPTHTTKDM4EKMT2AMEN1 | |
| SCHEMBL9823872 | 0.75 | ALDH1A1 (0.53) | HPGDCYP1A2CYP2C9ALOX15GAA | |
| SCHEMBL1259126 | 0.75 | POLB (0.38) | KMT2AMEN1POLB | |
| SCHEMBL17997263 | 0.75 | DGAT1 (0.54) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL4115726 | 0.74 | CA12 (0.55) | CES2GAAALDH1A1NPSR1 | |
| SCHEMBL29922210 | 0.74 | KDM4E (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008012-B | Compounds for the treatment of neuromuscular disorders | NMD制药股份公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114008012-A | Compounds for the treatment of neuromuscular disorders | NMD制药股份公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020254559-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2020-12-24 | — | — | WO | disclosed |