Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489409 | 0.80 | L3MBTL1 (0.66) | L3MBTL1MAPTALDH1A1GFERFGFR1 | |
| SCHEMBL211698 | 0.76 | L3MBTL1 (0.61) | L3MBTL1MAPTALDH1A1GFERFGFR1 | |
| SCHEMBL2031700 | 0.76 | MAPT (0.47) | L3MBTL1MAPTCYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL1631009 | 0.75 | MAPT (0.45) | L3MBTL1MAPTCYP1A2ALDH1A1HTT | |
| SCHEMBL31520666 | 0.75 | MAPT (0.45) | L3MBTL1MAPTCYP1A2ALDH1A1HTT | |
| SCHEMBL29921905 | 0.75 | MAPT (0.49) | L3MBTL1MAPTCYP1A2ALDH1A1POLB | |
| SCHEMBL29922141 | 0.74 | DDB1 (0.39) | L3MBTL1MAPTALDH1A1GFERGAA | |
| SCHEMBL29245836 | 0.74 | CYP1A2 (0.51) | L3MBTL1MAPTCYP1A2ALDH1A1MAPK1 | |
| SCHEMBL7708920 | 0.73 | MAPT (0.67) | L3MBTL1MAPTCYP1A2ALDH1A1HTT | |
| SCHEMBL19185810 | 0.73 | L3MBTL1 (1.00) | L3MBTL1MAPTALDH1A1FGFR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |