Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25339139 | 0.76 | ALDH1A1 (0.33) | MAPTKDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29922342 | 0.74 | L3MBTL1 (0.57) | MAPTALDH1A1GAAGFERL3MBTL1 | |
| SCHEMBL520854 | 0.74 | DYRK1A (0.60) | DDB1CRBNPRKCIMAPTKDM4E | |
| SCHEMBL29352067 | 0.74 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL1304538 | 0.74 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL29922331 | 0.71 | BRPF1 (0.45) | DDB1CRBNBRPF1PRKCIMAPT | |
| SCHEMBL212673 | 0.71 | MAPT (0.61) | PRKCIMAPTKDM4EALDH1A1GAA | |
| SCHEMBL28960449 | 0.70 | ALDH1A1 (0.45) | BRPF1MAPTKDM4EALDH1A1GAA | |
| SCHEMBL27473876 | 0.69 | PRKCI (0.40) | DDB1CRBNBRPF1PRKCIMAPT | |
| SCHEMBL31425543 | 0.69 | DYRK1A (0.39) | KDM4EDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |