SCHEMBL299230

SCHEMBL299230

Nc1ccccc1S(=O)(=O)Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.65
CA9 Q16790 3/20 0.62
CA1 P00915 3/20 0.62
CA2 P00918 3/20 0.62
CA4 P22748 3/20 0.62
CA12 O43570 2/20 0.62
CA6 P23280 2/20 0.62
CYP2C9 P11712 1/20 0.62
CA5A P35218 1/20 0.62
CA7 P43166 1/20 0.62
CA14 Q9ULX7 1/20 0.62
CA5B Q9Y2D0 1/20 0.62
HTR6 P50406 1/20 0.56
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KYNU Q16719 2/20 0.43
CYP3A4 P08684 1/20 0.43
ALOX15 P16050 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250199 0.81 ALDH1A1 (0.55) GAACA9CA1CA2CA4
SCHEMBL10585490 0.79 GAA (1.00) GAACA9CA1CA2CA4
SCHEMBL30223488 0.79 GAA (1.00) GAACA9CA1CA2CA4
SCHEMBL34423 0.79 GAA (1.00) GAACA9CA1CA2CA4
SCHEMBL28553999 0.78 CYP3A4 (0.62) GAACA9CA1CA2CA4
SCHEMBL10565795 0.78 SMN1; SMN2 (0.45) GAACA9CA1CA2CA4
SCHEMBL7484553 0.78 CYP3A4 (0.52) GAACA9CA1CA2CA4
SCHEMBL8516378 0.78 TTR (0.66) GAACA9CA1CA2CA4
Hydrochloric Acid SCHEMBL11745781 0.77 GAA (0.95) GAACA9CA1CA2CA4
SCHEMBL6003437 0.77 GAA (0.95) GAACA9CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021114460-A1 METHOD FOR PRODUCING P-ACETAMIDOBENZENESULFONYL CHLORIDE BY MEANS OF DOUBLE-TEMPERATURE-ZONE TWO-STAGE METHOD BASED ON CONTINUOUS FLOW REACTION 山东金德新材料有限公司 2021-06-17 WO claimed
CN-104961660-B A kind of acid inner salt compound of amidine 苏州大学张家港工业技术研究院 2017-06-13 CN claimed
CN-104945287-B A kind of synthetic method of the acid inner salt compound of amidine 苏州大学张家港工业技术研究院 2017-06-13 CN claimed
CN-104961660-A Inner salt compound of amidine sulfonic acid ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV 2015-10-07 CN claimed
CN-104945287-A Synthetic method of sulfonic acid inner salt compound of amidine ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV 2015-09-30 CN claimed
JP-51151293-A None JP disclosed
CN-116536940-B Affinity-convertible disperse reactive dye nonaqueous medium dyeing process 东华大学 2025-05-23 CN disclosed
CN-119241399-A Benzenesulfonyl compound taking AR/AR-V7 double protein as target point and preparation method and application thereof 上海应用技术大学 2025-01-03 CN disclosed
CN-116536940-A Affinity-convertible disperse reactive dye nonaqueous medium dyeing process 东华大学 2023-08-04 CN disclosed
CN-109384694-B SIRT6 small-molecule agonist and application thereof 上海爱乐维生物科技有限公司 2022-04-05 CN disclosed
US-20200055830-A1 3-ALKYL BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS Valo Health, LLC 2020-02-20 US disclosed
CN-109384694-A SIRT6 small molecule agonist and its application 上海交通大学医学院 2019-02-26 CN disclosed
US-4976891-A Antithrombotic, antivasoconstricting, antibronchoconstricting SHIONOGI & CO., LTD. (JP) 1990-12-11 US disclosed
US-4960909-A ANTICOAGULANTS; VASODILATORS; BRONCHODILATOR AGENTS SHIONOGI & CO., LTD. (JP) 1990-10-02 US disclosed
US-4861913-A Bicyclic sulfonamide derivatives SHIONOGI & CO., LTD. (JP) 1989-08-29 US disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed
EP-0262395-A2 Sulfonamido-ethyl compounds, medicines containing them and process for their preparation Dr. Karl Thomae GmbH (DE) 1988-04-06 EP disclosed
EP-0226346-A1 Bicyclic sulfonamide derivatives SHIONOGI & CO., LTD. (JP) 1987-06-24 EP disclosed
US-4558121-A Sulfoethylaminosulfonyl substituted disazo dyes CIBA GEIGY CORPORATION (US) 1985-12-10 US disclosed
JP-S51151293-A PROCESS FOR PURIFICATION AND RECOVERY OF THE SULFURIC ACID BY-PRODUCT NISSAN CHEM IND LTD 1976-12-25 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200055830-A1 3-ALKYL BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS HDAC1, HDAC4, HDAC2 GAA 89/4885CA9 1651/4885CA1 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.