Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279094 | 0.91 | ALDH1A1 (0.53) | SMN1; SMN2HTTALDH1A1HPGDCA1 | |
| SCHEMBL29350373 | 0.91 | ALDH1A1 (0.53) | SMN1; SMN2HTTALDH1A1HPGDCA1 | |
| SCHEMBL5178232 | 0.79 | CA1 (0.49) | CA1CA2CA9GAACA12 | |
| SCHEMBL299230 | 0.78 | GAA (0.65) | SMN1; SMN2ALDH1A1CA1CA2CA9 | |
| SCHEMBL4463532 | 0.77 | CA1 (0.70) | ALDH1A1HPGDCA1CA2CA9 | |
| SCHEMBL31309573 | 0.77 | CA1 (0.70) | ALDH1A1HPGDCA1CA2CA9 | |
| SCHEMBL9781016 | 0.76 | CA1 (0.55) | SMN1; SMN2HTTALDH1A1CA1CA2 | |
| SCHEMBL463597 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL29904721 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL7219508 | 0.76 | ALDH1A1 (0.52) | SMN1; SMN2HTTALDH1A1HPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861913-A | Bicyclic sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |