Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916133 | 1.00 | PSMB5 (0.35) | PSMB5PDGFRBPDGFRARXRAGRIN1 | |
| SCHEMBL29923857 | 0.77 | MAPT (0.34) | — | |
| SCHEMBL24916128 | 0.77 | MAPT (0.34) | — | |
| SCHEMBL24915595 | 0.77 | PSMB5 (0.33) | PSMB5PDGFRBPDGFRA | |
| SCHEMBL24916284 | 0.76 | MAPT (0.37) | — | |
| SCHEMBL31353505 | 0.75 | PSMB5 (0.37) | PSMB5PDGFRBPDGFRA | |
| SCHEMBL18123538 | 0.74 | CYP1A2 (0.41) | RXRAGRIN1GRIN2B | |
| SCHEMBL29923786 | 0.72 | PSMB5 (0.35) | PSMB5PDGFRBPDGFRA | |
| SCHEMBL24916495 | 0.72 | PSMB5 (0.35) | PSMB5PDGFRBPDGFRA | |
| SCHEMBL18123545 | 0.70 | KCNH2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |