Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916495 | 1.00 | PSMB5 (0.35) | PSMB5MTNR1BMTNR1APDGFRBPDGFRA | |
| SCHEMBL29923631 | 0.77 | CYP1A1 (0.36) | MTNR1BMTNR1APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL24916492 | 0.77 | CYP1A1 (0.36) | MTNR1BMTNR1APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL24915594 | 0.77 | MTNR1B (0.33) | PSMB5MTNR1BMTNR1APDGFRBPDGFRA | |
| SCHEMBL425260 | 0.76 | MTNR1B (0.49) | MTNR1BMTNR1APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL29923616 | 0.76 | MTNR1B (0.49) | MTNR1BMTNR1APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL31353505 | 0.75 | PSMB5 (0.37) | PSMB5PDGFRBPDGFRA | |
| SCHEMBL29923483 | 0.74 | KDM4E (0.41) | KDM4EMAOBEGFR | |
| SCHEMBL19776334 | 0.72 | MAPT (0.39) | ALDH1A1HPGDKDM4ECYP1A2CYP3A4 | |
| SCHEMBL24916133 | 0.72 | PSMB5 (0.35) | PSMB5PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |