Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916018 | 0.79 | PDE10A (0.31) | NR3C2 | |
| SCHEMBL21008176 | 0.77 | NR3C2 (0.40) | NR3C2 | |
| SCHEMBL24916133 | 0.77 | PSMB5 (0.35) | PSMB5PDGFRBPDGFRA | |
| SCHEMBL29923256 | 0.77 | PSMB5 (0.35) | PSMB5PDGFRBPDGFRA | |
| SCHEMBL24915594 | 0.74 | MTNR1B (0.33) | PSMB5PDGFRBPDGFRA | |
| SCHEMBL15417377 | 0.72 | DHFR (0.33) | — | |
| SCHEMBL18123538 | 0.71 | CYP1A2 (0.41) | — | |
| SCHEMBL24930878 | 0.68 | DHFR (0.33) | — | |
| SCHEMBL21173346 | 0.68 | ALDH1A1 (0.49) | — | |
| SCHEMBL18123545 | 0.68 | KCNH2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | PSMB5 400/4885NR3C2 2668/4885PDGFRB 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.