Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290743 | 0.93 | MAPK1 (0.58) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL23116611 | 0.81 | MAPK1 (0.67) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL10877541 | 0.76 | MAPK1 (0.67) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL29780037 | 0.73 | MAPK1 (0.68) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL12605546 | 0.71 | MAPK1 (0.83) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL2512199 | 0.71 | CDK4 (0.68) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL10165541 | 0.71 | LMNA (0.65) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL23844605 | 0.71 | LMNA (0.65) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL3596244 | 0.70 | LMNA (0.60) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL19148301 | 0.70 | LMNA (0.60) | MAPK1CYP1A2CYP3A4CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095042-A1 | Organic Compounds Having Cooling Properties | GIVAUDAN SA (CH) | 2012-04-19 | — | — | US | claimed |
| WO-2010128026-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | WO | claimed |
| US-8664261-B2 | Organic compounds having cooling properties | GIVAUDAN S.A. (CH) | 2014-03-04 | — | — | US | disclosed |
| US-8664261-B2 | Organic compounds having cooling properties | GIVAUDAN S.A. (CH) | 2014-03-04 | — | — | US | disclosed |
| US-20120095042-A1 | Organic Compounds Having Cooling Properties | GIVAUDAN SA (CH) | 2012-04-19 | — | — | US | disclosed |
| US-20120095042-A1 | Organic Compounds Having Cooling Properties | GIVAUDAN SA (CH) | 2012-04-19 | — | — | US | disclosed |
| EP-2427170-A2 | ORGANIC COMPOUNDS HAVING COOLING PROPERTIES | Givaudan SA (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128026-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128026-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095042-A1 | Organic Compounds Having Cooling Properties | ME3, ME2, MSMO1 | MAPK1 3114/4885CYP1A2 241/4885CYP3A4 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.