Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 17/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729998 | 1.00 | USP30 (0.48) | USP30DGAT1IDO1SOAT1FAAH | |
| SCHEMBL22729999 | 1.00 | USP30 (0.48) | USP30DGAT1IDO1SOAT1FAAH | |
| Bicarbonate SCHEMBL9280862 | 0.86 | IDO1 (0.54) | USP30IDO1 | |
| SCHEMBL21385234 | 0.84 | DGAT1 (0.46) | USP30DGAT1IDO1 | |
| SCHEMBL30209427 | 0.84 | DGAT1 (0.46) | USP30DGAT1IDO1 | |
| SCHEMBL21583831 | 0.83 | USP30 (0.44) | USP30DGAT1IDO1SOAT1FAAH | |
| SCHEMBL22755410 | 0.83 | LNPEP (0.46) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL9277352 | 0.81 | IDO1 (0.50) | USP30IDO1 | |
| SCHEMBL23660437 | 0.77 | IDO1 (0.48) | USP30IDO1 | |
| SCHEMBL22730013 | 0.77 | IDO1 (0.48) | USP30IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092750-B | Pentafluoro sulfanyl substituted amide compound, preparation method and application thereof in medicine | 北京诺诚健华医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-112334458-B | 3-indazolinone compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-11-08 | — | — | CN | disclosed |