Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL591893 | 1.00 | MAPT (0.56) | MAPTGRM1EGFRKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL28102779 | 0.98 | MAPT (0.55) | MAPTGRM1EGFRKDM4EPOLB | |
| SCHEMBL144584 | 0.86 | EGFR (0.54) | MAPTGRM1EGFRKDM4EPOLB | |
| SCHEMBL29461134 | 0.86 | EGFR (0.54) | MAPTGRM1EGFRKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL28824441 | 0.84 | EGFR (0.52) | MAPTGRM1EGFRKDM4EPOLB | |
| SCHEMBL28817807 | 0.83 | ENPP1 (0.55) | MAPTKDM4EENPP1MAP4K4ALDH1A1 | |
| SCHEMBL1012882 | 0.82 | FBP1 (0.53) | MAPTGRM1EGFRENPP1ALDH1A1 | |
| SCHEMBL12779098 | 0.80 | MAPT (0.58) | MAPTGRM1EGFRKDM4ECSF1R | |
| SCHEMBL535605 | 0.79 | ALDH1A1 (0.44) | MAPTKDM4EPOLBALDH1A1LMNA | |
| SCHEMBL7795285 | 0.79 | ENPP1 (0.45) | EGFRLCKENPP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622970-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2025007113-A2 | MITOCHONDRIAL COMPLEX I INHIBITORS WITH REDUCED PHOSPHODIESTERASE INHIBITION | OHIO STATE INNOVATION FOUNDATION (US) | 2025-01-02 | — | — | WO | disclosed |
| WO-2024112854-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |