Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28653479 | 1.00 | TDP1 (0.70) | TDP1NPC1RAB9AMAOBMAOA | |
| SCHEMBL29923812 | 0.89 | LMNA (0.66) | NPC1RAB9AMAOBMAOALMNA | |
| SCHEMBL28645521 | 0.89 | LMNA (0.66) | NPC1RAB9AMAOBMAOALMNA | |
| SCHEMBL29923723 | 0.87 | POLB (0.70) | NPC1RAB9AMAOBMAOALMNA | |
| SCHEMBL28642133 | 0.87 | POLB (0.70) | NPC1RAB9AMAOBMAOALMNA | |
| SCHEMBL23657482 | 0.83 | ALDH1A1 (0.55) | TDP1NPC1RAB9AMAOBMAOA | |
| SCHEMBL21174969 | 0.82 | LMNA (0.80) | TDP1NPC1RAB9ALMNAKDM4E | |
| SCHEMBL8645195 | 0.76 | LMNA (0.67) | NPC1RAB9AMAOBMAOALMNA | |
| SCHEMBL6633181 | 0.74 | CSNK2A2 (0.72) | NPC1RAB9AMAOBMAOALMNA | |
| SCHEMBL4970562 | 0.73 | MAOB (0.82) | NPC1RAB9AMAOBMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549043-B | Flavonoid tankyrase 2 inhibitor and preparation method and application thereof | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |