Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.45 |
| ▸ | PRNP | P04156 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966064 | 1.00 | ALDH1A1 (0.55) | ALDH1A1GAAKDM4EMAPTATM | |
| SCHEMBL15054414 | 0.85 | MPO (0.46) | ALDH1A1GAAKDM4EMAPTATM | |
| SCHEMBL3760247 | 0.81 | LMNA (0.61) | ALDH1A1GAAKDM4EMAPTTDP1 | |
| SCHEMBL15724648 | 0.81 | CYP1A2 (0.57) | ALDH1A1GAAKDM4EMAPTATM | |
| SCHEMBL30048942 | 0.81 | CYP1A2 (0.57) | ALDH1A1GAAKDM4EMAPTATM | |
| SCHEMBL6089328 | 0.81 | HTT (0.44) | ALDH1A1GAAKDM4EMAPTATM | |
| SCHEMBL4748554 | 0.78 | POLB (0.53) | ALDH1A1KDM4EHTTMPOKMT2A | |
| SCHEMBL3906125 | 0.78 | GAA (0.47) | ALDH1A1GAAKDM4EATMMPO | |
| SCHEMBL4966407 | 0.78 | LMNA (0.68) | ALDH1A1GAAKDM4EMAPTATM | |
| SCHEMBL3642253 | 0.78 | LMNA (0.41) | ALDH1A1GAAKDM4ECYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522616-A1 | LRRK2 INHIBITORS | Interline Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220247-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |