Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30134451 | 0.86 | KMT2A (0.58) | KMT2AMEN1ALDH1A1HTTEGLN1 | |
| SCHEMBL11804278 | 0.82 | NSD2 (0.58) | KMT2AMEN1ALDH1A1HTTEGLN1 | |
| SCHEMBL29923896 | 0.81 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1HTTEGLN1 | |
| SCHEMBL29923698 | 0.81 | PARP1 (0.58) | KMT2AMEN1ALDH1A1HTTEGLN1 | |
| SCHEMBL20515224 | 0.81 | PARP1 (0.58) | KMT2AMEN1ALDH1A1HTTEGLN1 | |
| SCHEMBL8101444 | 0.80 | NPC1 (0.59) | KMT2AMEN1ALDH1A1KDM4ETP53 | |
| SCHEMBL29923828 | 0.79 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1HTTEGLN1 | |
| SCHEMBL29923665 | 0.78 | KMT2A (0.52) | KMT2AMEN1ALDH1A1HTTEGLN1 | |
| SCHEMBL29923608 | 0.78 | KMT2A (0.50) | KMT2AMEN1ALDH1A1HTTEGLN1 | |
| SCHEMBL24915856 | 0.77 | JAK2 (0.42) | KMT2AALDH1A1EGLN1KDM4ERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |