Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | MET | P08581 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | TEK | Q02763 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923828 | 0.88 | ALDH1A1 (0.53) | ALDH1A1EGLN1KMT2AMEN1HDAC1 | |
| SCHEMBL30134451 | 0.83 | KMT2A (0.58) | ALDH1A1EGLN1KMT2AMEN1POLB | |
| SCHEMBL22750329 | 0.83 | MEN1 (0.60) | ALDH1A1EGLN1KMT2AMEN1POLB | |
| SCHEMBL29923746 | 0.81 | KMT2A (0.56) | ALDH1A1EGLN1KMT2AMEN1HDAC1 | |
| SCHEMBL29923608 | 0.80 | KMT2A (0.50) | ALDH1A1EGLN1KMT2AMEN1AURKA | |
| SCHEMBL11804278 | 0.79 | NSD2 (0.58) | ALDH1A1EGLN1KMT2AMEN1HDAC1 | |
| SCHEMBL29923698 | 0.78 | PARP1 (0.58) | ALDH1A1EGLN1KMT2AMEN1HDAC1 | |
| SCHEMBL20515224 | 0.78 | PARP1 (0.58) | ALDH1A1EGLN1KMT2AMEN1HDAC1 | |
| SCHEMBL24915850 | 0.77 | KDM4E (0.47) | ALDH1A1EGLN1KMT2AMEN1AURKA | |
| SCHEMBL29923665 | 0.76 | KMT2A (0.52) | ALDH1A1EGLN1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |