Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 2/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804278 | 0.84 | NSD2 (0.58) | KMT2AALDH1A1MEN1CASP7CASP6 | |
| SCHEMBL29923698 | 0.83 | PARP1 (0.58) | KMT2AALDH1A1MEN1CASP7CASP6 | |
| SCHEMBL20515224 | 0.83 | PARP1 (0.58) | KMT2AALDH1A1MEN1CASP7CASP6 | |
| SCHEMBL30134451 | 0.81 | KMT2A (0.58) | KMT2AALDH1A1MEN1CASP7CASP6 | |
| SCHEMBL29923746 | 0.78 | KMT2A (0.56) | KMT2AALDH1A1MEN1CASP7CASP6 | |
| SCHEMBL4961749 | 0.77 | PARP1 (0.62) | KMT2AALDH1A1MEN1CASP3HTT | |
| SCHEMBL6071988 | 0.76 | MAPT (0.60) | KMT2AALDH1A1MEN1CASP6HTT | |
| SCHEMBL29923896 | 0.76 | ALDH1A1 (0.55) | KMT2AALDH1A1MEN1HTTEGLN1 | |
| SCHEMBL6573464 | 0.74 | KDM4E (0.65) | KMT2AALDH1A1MEN1CASP7CASP6 | |
| SCHEMBL24915857 | 0.74 | LMNA (0.39) | CASP7CASP6NSD2CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |