Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073416 | 0.83 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1CCR1CCR5CCR8 | |
| SCHEMBL2270856 | 0.82 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1CCR1CCR5CCR8 | |
| SCHEMBL24916289 | 0.81 | NSD2 (0.50) | CCR1CCR5CCR8KDM4ENOS3 | |
| SCHEMBL24916103 | 0.80 | NOS3 (0.41) | HSP90AA1CCR1CCR5CCR8KDM4E | |
| SCHEMBL29923344 | 0.80 | CCR1 (0.39) | HSP90AA1HSP90AB1CCR1CCR5CCR8 | |
| SCHEMBL29924149 | 0.80 | NOS3 (0.41) | HSP90AA1CCR1CCR5CCR8KDM4E | |
| SCHEMBL31392519 | 0.79 | KDM4E (0.39) | HSP90AA1HSP90AB1CCR1CCR5CCR8 | |
| SCHEMBL25130366 | 0.75 | ALOX5AP (0.39) | HSP90AA1HSP90AB1KDM4EDYRK1ACYP3A4 | |
| SCHEMBL31728793 | 0.75 | KDM4E (0.49) | KDM4EPOLBCYP1A1CYP1B1KMT2A | |
| SCHEMBL5262975 | 0.73 | PDGFRB (0.42) | CCR1CCR5CCR8KDM4ENOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |