Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B17 | O75795 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915886 | 0.82 | MTNR1B (0.32) | MTNR1BMTNR1A | |
| SCHEMBL24916199 | 0.82 | MTNR1B (0.32) | MTNR1BMTNR1A | |
| SCHEMBL24916120 | 0.81 | ACHE (0.37) | — | |
| SCHEMBL24916100 | 0.81 | PDGFRB (0.34) | MTNR1B | |
| Hydrochloric Acid SCHEMBL29923942 | 0.80 | ACHE (0.36) | — | |
| Hydrochloric Acid SCHEMBL29923527 | 0.80 | ACHE (0.36) | — | |
| SCHEMBL24916201 | 0.79 | HPGDS (0.32) | PDK2MTNR1BMTNR1ANQO2 | |
| SCHEMBL10376874 | 0.79 | UGT2B17 (0.53) | UGT2B17GRM5 | |
| SCHEMBL20554141 | 0.76 | UGT2B17 (0.38) | UGT2B17GRM5 | |
| SCHEMBL15309331 | 0.76 | UGT2B17 (0.38) | UGT2B17GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |