Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 10/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916099 | 1.00 | WDR5 (0.42) | WDR5PDE3BPDE3ANTRK1GAA | |
| SCHEMBL29923684 | 0.89 | WDR5 (0.40) | WDR5PDE3BPDE3ANTRK1BRD4 | |
| SCHEMBL24916095 | 0.87 | WDR5 (0.39) | WDR5ALDH1A1POLBMAPTNPSR1 | |
| SCHEMBL30054457 | 0.82 | WDR5 (0.46) | WDR5PDE3BPDE3ABRD4CREBBP | |
| SCHEMBL24916117 | 0.82 | WDR5 (0.46) | WDR5PDE3BPDE3ABRD4CREBBP | |
| SCHEMBL27167325 | 0.82 | WDR5 (0.44) | WDR5PDE3BPDE3AGAAALDH1A1 | |
| SCHEMBL24915754 | 0.80 | WDR5 (0.46) | WDR5PDE3BPDE3ABRD4 | |
| SCHEMBL30055237 | 0.80 | WDR5 (0.46) | WDR5PDE3BPDE3ABRD4 | |
| SCHEMBL29923286 | 0.78 | PARP1 (0.48) | WDR5PDE3BPDE3A | |
| SCHEMBL24916292 | 0.75 | WDR5 (0.54) | WDR5PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334305-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022236101-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY (US) | 2022-11-10 | — | — | WO | disclosed |
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |