Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 4/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435955 | 0.93 | SCD (0.39) | EIF4EMKNK1MKNK2SCDEPHX2 | |
| SCHEMBL22203193 | 0.93 | SCD (0.39) | EIF4EMKNK1MKNK2SCDEPHX2 | |
| SCHEMBL874170 | 0.79 | NPY1R (0.47) | PDE4BCSNK2A1PDE4APDE4CPDE4D | |
| SCHEMBL23099857 | 0.79 | EIF4E (0.40) | EIF4EMKNK1MKNK2SCDCSNK2A1 | |
| SCHEMBL15534488 | 0.79 | MCHR1 (0.42) | EIF4EMKNK1MKNK2PDE4BSCD | |
| SCHEMBL24925307 | 0.79 | EIF4E (0.43) | EIF4EMKNK1MKNK2SCDCSNK2A1 | |
| SCHEMBL20064064 | 0.78 | FFAR4 (0.45) | EIF4EMKNK1MKNK2SCDEPHX2 | |
| SCHEMBL2908060 | 0.77 | PDE4A (0.51) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL873580 | 0.77 | CA1 (0.45) | PDE4BPDE4APDE4CPDE4DMCHR1 | |
| SCHEMBL23250796 | 0.77 | SCD (0.37) | EIF4EMKNK1MKNK2SCDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390745-B | Pyridine nicotinamide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-10-21 | — | — | CN | disclosed |