SCHEMBL29924210

SCHEMBL29924210

S=C1CCc2ccc(-c3ccc(Cl)c(Cl)c3)cc2N1CCN1CCOCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.47
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 1/20 0.43
SLC6A3 Q01959 2/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
GAA P10253 2/20 0.41
CNR2 P34972 1/20 0.40
MAPK13 O15264 1/20 0.40
MAPK12 P53778 1/20 0.40
MAPK11 Q15759 1/20 0.40
MAPK14 Q16539 1/20 0.40
MEN1 O00255 2/20 0.39
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
TSHR P16473 2/20 0.39
NPC1 O15118 1/20 0.39
USP2 O75604 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28901298 1.00 SIGMAR1 (0.47) SIGMAR1ALDH1A1KDM4ESLC6A3SLC6A2
SCHEMBL29924454 0.86 SIGMAR1 (0.47) SIGMAR1ALDH1A1KDM4ESLC6A3SLC6A2
SCHEMBL28901360 0.86 SIGMAR1 (0.47) SIGMAR1ALDH1A1KDM4ESLC6A3SLC6A2
SCHEMBL29924446 0.83 CYP1A2 (0.41) SIGMAR1NPC1RAB9ASMN1; SMN2
SCHEMBL28901323 0.83 CYP1A2 (0.41) SIGMAR1NPC1RAB9ASMN1; SMN2
SCHEMBL28901351 0.75 ADRA1B (0.47) SIGMAR1TSHR
SCHEMBL29924398 0.75 ADRA1B (0.47) SIGMAR1TSHR
SCHEMBL29924292 0.71 DRD2 (0.52) HPGD
SCHEMBL28901320 0.71 DRD2 (0.52) HPGD
SCHEMBL28901318 0.71 DRD2 (0.52) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073370-A Novel alkylammonium compound or salt, isomer, preparation method and application thereof 成都硕德药业有限公司 2022-09-20 CN claimed
CN-115073370-B Novel alkylaminos or salts, isomers, preparation method and application thereof 成都硕德药业有限公司 2024-12-17 CN disclosed
CN-115073370-A Novel alkylammonium compound or salt, isomer, preparation method and application thereof 成都硕德药业有限公司 2022-09-20 CN disclosed